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Extra virgin coconut oil (Cocos nucifera L.) exerts anti-obesity effect by modulating adiposity and improves hepatic lipid metabolism, leptin and insulin resistance in diet-induced obese rats

Maria Helena Araujo de Vasconcelos,Renata Leite Tavares,Emanuel Ubaldino Torres Junior,Victor Augusto Mathias Dorand,Kamila Sabino Batista,Lydiane Tavares Toscano,Alexandre Sergio Silva,Angela Maria Tribuzy de Magalhaes Cordeiro,Bruno Ranieri Lins de Albuquerque Meireles,Rubens da Silva Araujo,Adriano Francisco Alves,Jailane de Souza Aquino

Journal of Functional Foods（2022）

Cited 6|Views7
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Abstract
•E-VCO is rich in rutin, 3,4-dihydroxybenzoic acid, salicylic acid and quercetin.•Bioactive compounds in E-VCO reduced insulin, leptin and HOMA-IR in obese rats.•E-VCO administration reduced adiposity index and adipocytes area in obese rats.•E-VCO minimized cholesterol and triglyceride hepatic levels and hepatic steatosis.
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Key words
Adiposity,Antioxidants,Cafeteria diet,Insulin,Leptin,Lipid metabolism
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