Photocatalyst-free visible light induced decarboxylative alkylation of quinoxalin-2(1H)-ones with carboxylic acids

Using commercially available and cheap carboxylic acids as alkylating reagents, a practical methodology for the visible-light induced decarboxylative alkylation of quinoxalin-2(1H)-ones was developed. The reaction proceeds in the absence of metal-catalyst, acid or basic additive, or external photosensitizer, making it an environmentally friendly and attractive protocol for the alkylation of quinoxalines. (C) 2021 Elsevier Ltd. All rights reserved.