Neighborhood disadvantage, health status, and healthcare utilization after blood or marrow transplant: BMTSS report

Living in a disadvantaged neighborhood is associated with poor health outcomes. Blood or Marrow Transplant (BMT) survivors remain at risk of chronic health conditions requiring anticipatory management. We hypothesized that among BMT survivors, neighborhood disadvantage was associated with poor self-reported routine healthcare utilization and health. We leveraged data from BMTSS - a retrospective cohort study examining long-term outcomes among individuals surviving ≥2y following BMT at three institutions between 1974-2014. Participants in this analysis completed the BMTSS survey (sociodemographics; chronic health conditions; time since routine check-up; self-reported health). The Area Deprivation Index (ADI) represented neighborhood disadvantage; this composite indicator of 17 census measures is a percentile rank (0=least deprived to 100=most deprived). Multivariable ordered logit regression adjusted for clinical factors and individual-level sociodemographics, modeling associations between ADI, time since routine check-up, and self-reported health. Among 2,857 survivors, median ADI was 24 (interquartile range: 10-46). Adjusting for self-reported individual-level socioeconomic indicators and chronic health conditions, patients in more disadvantaged neighborhoods had higher odds of reporting longer intervals since routine check-up (ORADI_continuous=1.007, p<0.001) and poorer health status (controlling for time since check-up; ORADI_continuous=1.005, p=0.003). Compared to patients living in the least disadvantaged neighborhood (ADI=1), patients in the most disadvantaged neighborhood (ADI=100), had twice the odds (ORADI=1.007^99=2.06) of reporting no routine visits and 1.65-times the odds of reporting poor health (ORADI=1.005^99=1.65). In BMT survivors, access to healthcare and health status are associated with area disadvantage. These findings may inform strategies to address long-term care coordination and retention for vulnerable survivors.