Cardiovascular Disease in Duchenne Muscular Dystrophy: Overview and Insight Into Novel Therapeutic Targets

Taylor I. Schultz,Frank J. Raucci,Fadi N. Salloum

JACC: Basic to Translational Science(2022)

引用 12|浏览11
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摘要
•Cardiomyopathy is the leading cause of death in patients with DMD.•DMD has no cure, and there is no current consensus for treatment of DMD cardiomyopathy.•This review discusses therapeutic strategies to potentially reduce or prevent cardiac dysfunction in DMD patients.•Additional studies are needed to firmly establish optimal treatment modalities for DMD cardiomyopathy.
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关键词
arrhythmias,cardiomyopathy,Duchenne muscular dystrophy,inflammatory modulators,myocardial fibrosis
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