Controlling Herpes Simplex Virus-Induced Immunoinflammatory Lesions Using Metabolic Therapy: a Comparison of 2-Deoxy- d -Glucose with Metformin

Journal of Virology(2022)

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摘要
Herpes simplex virus (HSV) infection of the eye is an example where damaging lesions are in part the consequence of a host response to the infection. Moreover, it was shown that changing the representation of cellular participants in the inflammatory reaction can minimize lesion severity.
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关键词
herpes simplex virus, HSV-1, metformin, 2-deoxy-d-glucose, 2DG, herpetic stromal keratitis, HSK, encephalitis
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