Akkermansia Muciniphila Ameliorates Chronic Kidney Disease Interstitial Fibrosis Via the Gut-Renal Axis

Tingting Pei,Mingqing Wang,Rong Hu,Fujing Wang,Sixia Yang, Haitong Feng, Qiye Li,Jiaxing Zhang,Shihua Yan,Liliang Ju,Zhuoen He,Zhongxiao Han,Aicheng Yang,Yun Ma,Wei Xiao

SSRN Electronic Journal（2022）

引用 6|浏览9

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摘要

We found that Akkermansia muciniphila improved renal function in rats with chronic kidney disease.•Akkermansia muciniphila restores disturbed gut microbiome in rats with chronic kidney disease.•Akkermansia muciniphila improves the intestinal mucosal barrier and the level of inflammation in the body.•Akkermansia muciniphila improves interstitial fibrosis in chronic kidney disease.

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关键词

Chronic kidney disease,Intestinal barrier,Akkermansia muciniphila,Intestinal microecology,Renal interstitial fibrosis

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