Insights from an electro-mechanical heart failure cell model: Role of SERCA enhancement on arrhythmogenesis and myocyte contraction.

Maria Teresa Mora,Antonio Zaza,Beatriz Trenor

Computer methods and programs in biomedicine（2023）

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摘要

These simulated results encourage the development of strategies comprising SERCA stimulation and highlight the need to evaluate both electrical and mechanical outcomes.

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关键词

Computational modeling,Early afterdepolarizations,Electro-mechanics,Heart failure,SERCA,Twitch force

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