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Blocking the Farnesyl Pocket of PDEδ Reduces Rheb-Dependent Mtorc1 Activation and Survival of Tsc2-Null Cells.

Marisol Estrella Armijo,Emilia Escalona,Daniela Pena,Alejandro Farias,Violeta Morin,Matthias Baumann,Bert Matthias Klebl,Roxana Pincheira,Ariel Fernando Castro

Frontiers in Pharmacology（2022）

Cited 1|Views25
Key words
Rheb,PDE delta inhibitor,Deltasonamide 1,Tsc2-null cells,mTORC1 signaling
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