STUDY OF IRRITATING AND ALLERGENIC EFFECT OF GENTABIFERON-S WITH ITS A SINGLE DOSE AND REPEATED APPLICATION

Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine(2022)

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Abstract
In this research, we studied the irritating and allergenic effect of the drug Gentabiferon-S with its single dose and repeated administration in laboratory animals. It has been found that the drug does not cause irritation when installed on the conjunctiva and has a weak irritating effect when applied to the skin of rabbits on one occasion. In rare cases when applied, an allergic reaction may develop manifested in a short-term redness of the conjunctiva. With the increased dosage, the risk of type III hypersensitivity development increases.
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Key words
allergenic effect,single dose
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