mTOR Inhibition Abrogates Human Mammary Stem Cells and Early Breast Cancer Progression Markers

Hakim Bouamar,Larry Esteban Broome,Kate Lathrop,Ismail Jatoi,Andrew J. Brenner,Alia Nazarullah,Karla M. Gorena,Michael Garcia,Yidong Chen, Virginia Kaklamani,LuZhe Sun

SSRN Electronic Journal（2022）

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摘要

Overall, these findings indicate a link from mTOR signaling to mammary stem and progenitor cell activity and cancer progression. Trial registration This study involves a clinical trial registered under the ClinicalTrials.gov identifier NCT02642094 registered December 30, 2015.

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