Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition.

Julie Bonnereau,Tristan Courau,Nicolas Asesio, Delphine Salfati,Fatiha Bouhidel,Hélène Corte, Sarah Hamoudi,Nassim Hammoudi, Julie Lavolé,Justine Vivier-Chicoteau,Victor Chardiny, Leon Maggiori,Mathieu Blery,Romain Remark,Cécile Bonnafous,Pierre Cattan, Antoine Toubert,Purnima Bhat,Matthieu Allez,Thomas Aparicio,Lionel Le Bourhis

Gut（2023）

引用 6|浏览45

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摘要

In CRC, CD39 is strongly expressed on tumour infiltrating lymphocytes and its inhibition represents a promising therapeutic strategy for treating patients.

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关键词

CANCER IMMUNOBIOLOGY,COLORECTAL CANCER,EPITHELIAL CELLS,IMMUNOTHERAPY,INTESTINAL T CELLS

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