A Rare Etiology for Ascending Paralysis in an Infant

Keisuke Abe,Chanel Casamina,Natascha Ching,Keith K Abe,Marian Melish,Karen S Thompson,Asim A Ahmed,Prashant J Purohit

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY（2022）

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摘要

An 11-month-old male infant with ascending paralysis had an unremarkable initial cerebrospinal fluid (CSF) analysis and imaging. Progressive neurological symptoms resulted in repeated CSF sampling-microscopy, and plasma microbial cell-free DNA next-generation sequencing analysis, which in combination with epidemiology, confirmed the diagnosis. An 11-month-old male infant with ascending paralysis had an unremarkable initial cerebrospinal fluid (CSF) analysis and imaging. Progressive neurological symptoms resulted in repeated CSF sampling, microscopy, and plasma microbial cell-free DNA next-generation sequencing analysis, that in combination with epidemiology, confirmed the diagnosis.

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关键词

Angiostrongylus cantonensis, ascending -paralysis, eosinophilia, eosinophilic encephalomyelitis, -next-generation sequencing test, rat lungworm

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