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Sphingosine Kinase-1 (SPHK1) promotes inflammation in infantile pneumonia by regulating NLRP3 inflammasome and SIRT1 expression.

Niu Ding,Yanni Meng, Lianhong Liu,Song Ma,Yanping Chen

Histology and histopathology（2022）

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Abstract
Our study demonstrated that SPHK1 promotes inflammation of infantile pneumonia by modulating NLRP3 inflammasome via the regulation of SIRT1 expression and mitochondrial permeability transition.
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Key words
SPHK1,Infantile pneumonia,NLRP3,SIRT1
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