Medicinal Immunoglobulin G Products (2020) Show High Infectivity Neutralizing Activity Against Seasonal Influenza Virus Strains Selected for Future Vaccines (2020-2022)

José María Díez,Daniel Casals,Carolina Romero,Rodrigo Gajardo

OPEN FORUM INFECTIOUS DISEASES（2022）

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摘要

Immunoglobulin (Ig)G medicinal products manufactured in 2020 were tested for infectivity neutralization and hemagglutination inhibition against World Health Organization-selected influenza strains included in worldwide vaccines 2020-2022. The IgG batches (from US plasma) showed potent activity. Intravenous immunoglobulin could potentially add to therapies for serious influenza cases in immunocompromised patients. Further study is warranted.

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关键词

antibody neutralization, hemagglutination, IgG medicinal products, influenza, vaccination

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