Safety of High-Dose Nasal Theophylline Irrigation in the Treatment of Postviral Olfactory Dysfunction: a Dose-Escalation Study

Jake J. Lee,Shruti Gupta,Dorina Kallogjeri,Jay F. Piccirillo

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY（2022）

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摘要

This case series aims to determine the maximum tolerable dose of theophylline delivered via high-volume, low-pressure nasal saline irrigation for treatment of postviral olfactory dysfunction.

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