Small molecules enhancers of amyloid aggregation of C-terminal domain of Nucleophosmin 1 in acute myeloid leukemia
Bioorganic Chemistry(2022)
Abstract
•Enhancing effects of small molecules on the amyloid aggregation of CTD of NPMc+.•Morphological changes of amyloid fibers induced by small molecules.•Effects of small molecules on cell viability of leukemic cell lines.
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Key words
Small molecules,Aggregation,Amyloid fibers,Acute myeloid leukemia
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