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Small molecules enhancers of amyloid aggregation of C-terminal domain of Nucleophosmin 1 in acute myeloid leukemia

Daniele Florio,Valentina Roviello,Sara La Manna,Fabiana Napolitano,Anna Maria Malfitano,Daniela Marasco

Bioorganic Chemistry（2022）

Cited 5|Views8
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Abstract
•Enhancing effects of small molecules on the amyloid aggregation of CTD of NPMc+.•Morphological changes of amyloid fibers induced by small molecules.•Effects of small molecules on cell viability of leukemic cell lines.
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Key words
Small molecules,Aggregation,Amyloid fibers,Acute myeloid leukemia
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