Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, in vitro cytotoxic activity and their DNA damage determination
Bioorganic Chemistry(2022)
Abstract
•Synthesis of new hexa-substituted cyclotriphosphazene derivatives.•All the compounds were characterized by using spectroscopy methods.•In-vitro cytotoxicity properties of all new derivatives were performed.•In-vitro DNA damage evaluation of all new derivatives were performed.
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Key words
Cyclotriphosphazene,Cytotoxicity,Genotoxicity,Chalcones,Synthesis
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