Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, in vitro cytotoxic activity and their DNA damage determination

•Synthesis of new hexa-substituted cyclotriphosphazene derivatives.•All the compounds were characterized by using spectroscopy methods.•In-vitro cytotoxicity properties of all new derivatives were performed.•In-vitro DNA damage evaluation of all new derivatives were performed.