Amelioration of oxidative stress mediated inflammation and apoptosis in pancreatic islets by Lupeol in STZ-induced hyperglycaemic mice

Abhishek Kumar Das,Uday Hossain,Sumit Ghosh, Sima Biswas,Mullicka Mandal,Bhagirath Mandal,Goutam Brahmachari,Angshuman Bagchi,Parames C Sil

Life Sciences（2022）

引用 6|浏览6

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摘要

•Lupeol exhibits anti-diabetic effects against hyperglycaemic mice.•Lupeol protects against streptozotocin induced pancreatic toxicity.•Lupeol protects against oxidative pressure, inflammation and apoptosis in pancreas.

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BCA,CAT,DM,DNA,DNPH,DTT,ECL,EDTA,ELISA,GAPDH,HEPES,HRP,Iκ-Bα,IL-1β,MD2,MDA,NADH,NF-κB,PBS,PMSF,RIPA,RNA,ROS,RT-PCR,SDS,SOD,STZ,TBA,TBARS,TCA,TLR2,TLR4,TNF-α,TNF-R1

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