IFN alpha Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk

Cancer discovery(2022)

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摘要
In this issue, Hu and colleagues unveil that IFN alpha administration combined with anti-PD-1 therapy can potentiate murine and human CD8(+) T-cell antitumor response in hepatocellular carcinoma, highlighting a novel therapeutic strategy for hepatocellular carcinoma.
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