Roux-en-Y gastric bypass with a long versus a short biliopancreatic limb improves weight loss and glycemic control in obese mice.

Romano Schneider,Marko Kraljević,Ralph Peterli,Theresa V Rohm,Angela J T Bosch,Andy J Y Low,Lena Keller,Shefaa AlAsfoor,Simon Häfliger,Bahtiyar Yilmaz,Caspar J Peterson,Ioannis I Lazaridis,Pascale Vonaesch,Tarik Delko,Claudia Cavelti-Weder

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery（2022）

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Abstract

In obese mice, a long BPL results in enhanced weight loss and improved glucose tolerance. These findings could potentially be translated to humans by tailoring the BPL length according to body weight, obesity-related co-morbidities, and total bowel length of an individual patient.

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Key words

Gastric bypass,Gut physiology,Morbid obesity,RYGB animal model,Small bowel

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