A Case of Primary Pleural Synovial Sarcoma

We present here the case of a 29-year-old male with primary pleural synovial sarcoma.The patient had no complaints, no significant medical history and did not smoke.A well-circumscribed giant mass, adjacent to the chest wall was observed on a PA chest X-ray, with a solid mass lesion in the lateral right hemithorax with diffuse amorphous calcifications noted on thorax computed tomography.An F18-FDG uptake with a SUVmax of 5.0 was detected in the mass defined by PET/CT.A Tru-cut biopsy revealed monophasic as histological subtypes composed of a dense cellular and interlaced fascicular proliferation of spindle cells, and SYT-SSX1 fusion (X;18)(p11.23;q11)consistent with synovial sarcoma.The patient was followed-up in the oncology center after surgery and chemoradiotherapy, and has been stable for 1 year.This paper draws attention to a diagnostic approach to primary pleural synovial sarcoma, which is a rare and aggressive tumor, and the need for the prompt initiation of treatment for an improved outcome.