A Metal-free Access to Hindered N-Alkyl Sulfoximines via In-Situ Generated Aza-Oxyallyl Cations from Functionalized Alkyl Bromide

Herein, we report a catalyst-free and mild synthetic method for the construction of hindered N-alkyl sulfoximines derivative. A wide range of hindered di-alkyl sulfoximines can be readily obtained from the reaction of alpha-bromo-hydroxamates with a variety of sulfoximines, including diaryl, aryl-alkyl, di-alkyl and heteroaryl sulfoximines.