Longitudinal association between moderate to vigorous physical activity and lipid profile indicators in adolescents.

The objective of this study was to examine the association between time engaged in moderate (MPA), vigorous (VPA), and moderate-to-vigorous (MVPA) physical activity (PA) and indicators of lipid profile in adolescents. This longitudinal study with a four-year follow-up (2014 to 2017), and three collection points (2014, 2015 and 2017) analyzed the data of 136 adolescents aged between 10 and 13 years (53.7% girls), in João Pessoa, Paraíba state, Brazil. The time in MPA, VPA and MVPA times was measured by Actigraph GT3X+ accelerometers. The lipid profile indicators analyzed were total cholesterol (TC), low-density (LDL-C) and high-density lipoproteins cholesterol (HDL-C), triglycerides (TG), non-HDL-C, TC/HDL-C and TG/HDL-c ratios. A generalized estimating equation (GEE) model was used to analyze the association between PA and lipid profile indicators. There was an inverse association between MPA time and TC values (ß = -0.560; 95%CI: -1.116; -0.004); VPA and LDL-C (ß = -0.962; 95%CI: -1.678; -0.246) and non-HDL-C (ß = -0.955; 95%CI: -1.708; -0.201); and MVPA and TC (ß = -0.436; 95%CI: -0.816; -0.055), TG (ß = -0.415; 95%CI: -0.712; -0.118), LDL-C (ß = -0.460; 95%CI: -0.823; -0.096), non-HDL-C (ß = -0.522; 95%CI: -0.908; -0.136) and TC/HDL-C (ß = -0.472; 95%CI: -0.889; -0.055). We conclude that over 4 years, adolescents more engaged in PA, especially in MVPA, exhibited better levels of TC, TG, LDL-C, non-HDL-C and TC/HDL-C; and AFV exerted a greater influence on LDL-c and non-HDL-c levels.