[Prevention of adverse prognosis of malignant melanoma from the point of evolution of surgical margin].

Treating malignant melanoma of skin at the early stage depends on wide excision mainly. For the prevention of tumor recurrence, means of acquisition of the safe margin changed from empirical resection to accurate pathological evaluation, and therapeutic target evolved from clearing tumor cells to pursuing the best prognosis. In the future, it would be necessary to combine individualized treatment with evidence-based medicine in the treatment of cutaneous malignant melanoma to prevent adverse outcomes.