Enantioselective synthesis of isoxazole‐containing spirooxindole tetrahydroquinolines via squaramide‐catalysed cascade reactions
Organic & Biomolecular Chemistry（2022）
摘要
A class of o‐sulfonylaminostyryl isoxazole synthons were designed and demonstrated to be useful building blocks in asymmetric cascade aza‐Michael/Michael reaction with 3‐olefinic oxindoles. This squaramide‐catalysed cascade reaction afforded structurally complex...
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关键词
enantioselective synthesis,cascade reactions,isoxazole-containing,squaramide-catalysed
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