Combined immunotherapeutic effect of Leishmania-derived recombinant aldolase and Ambisome against experimental visceral leishmaniasis

Keerti,Narendra Kumar Yadav,Sumit Joshi,Sneha Ratnapriya,Amogh Anant Sahasrabuddhe,Anuradha Dube

Journal of Microbiology, Immunology and Infection（2023）

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摘要

Our experimental findings demonstrated that the chemo-immunotherapeutic approach could be an effective way of controlling human VL infection at minimal dosages of antileishmanial with reduced side-effects and propensity of drug resistance emergence.

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关键词

Ambisome,Chemo-immunotherapy,Hamster,Leishmania donovani and Recombinant aldolase (rLdAld)

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