Subxiphoid and subcostal arch versus unilateral video-assisted thoracic surgery approaches to thymectomy for myasthenia gravis

Yujiang Li, Zhenhui Huang, Wohua Han, Jingquan Yuan, Ruiwen Xie, Guobiao Cheng,Xi’an Huang, Yuliang Guo,Mongying Sun, Yali Liu,Xu Wu,Jianping Zhou

Surgery today(2022)

Cited 1|Views11
No score
Abstract
Purpose Thymectomy is an important treatment for myasthenia gravis (MG). We conducted this study to compare the clinical outcomes of the recently introduced subxiphoid and subcostal arch thymectomy (SASAT) approach with those of the standard unilateral video-assisted thoracoscopic surgery (VATS). Methods We analyzed, retrospectively, the perioperative, and long-term outcomes of 179 consecutive MG patients (age 18–65 years), who underwent SASAT or unilateral VATS-extended thymectomy between July, 2012 and May, 2019. Results All demographic and clinical characteristics were comparable in the two groups. The median surgical time, estimated blood loss, thoracotomy conversion rate, total and chest drainage, and complications did not differ significantly between the groups. The visual analog scale (VAS) score was significantly lower in the SASAT group. Complete stable remission (CSR) was achieved in a significantly larger proportion of the SASAT group patients and was significantly higher in women than in men. The Quantitative MG score was significantly lower in the SASAT group. Patients in the MG Foundation of America Clinical Classification groups I and II achieved better remission rates than those in groups III–V. Conclusions SASAT is a safe and feasible MG treatment, which may yield better outcomes than unilateral VATS and improve the quality of treatment.
More
Translated text
Key words
Myasthenia gravis (MG),Subxiphoid approach,Thymectomy
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined