2,5-Diketopiperazines: A Review of Source, Synthesis, Bioactivity, Structure, and MS Fragmentation.

Jia Jia,Jianling Yao,Jiao Kong,Axiang Yu,Jing Wei,Ying Dong,Ruolan Song,Dongjie Shan,Xiangjian Zhong,Fang Lv,Qiqi Fan,Gaimei She

Current medicinal chemistry（2023）

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摘要

As a category of relatively unexplored compounds, DKPs have been demonstrated to have various bioactivities, especially with antitumor and antibacterial activities. However, the existing research on DKPs is still in the early stage, and their application in drug development needs to be further studied.

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关键词

2,5-Diketopiperazines,bioactivity,cyclic dipeptides,fragmentation,mass spectrometry,mass spectrum fragmentation pattern

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