Extracellular Vesicles Released During Normothermic Machine Perfusion Are Associated With Human Donor Kidney Characteristics

Wouter Woud,Asel Arykbaeva,Ian Alwayn,Carla C. Baan,Robert Minee,Martin J. Hoogduijn,Karin Boer

Transplantation（2022）

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摘要

Our findings demonstrate that discarded expanded-criteria donor kidney grafts release distinct EV subsets during NMP. Because these subsets correlate with well-established indicators of transplant outcome, EVs might represent new potential candidates for assessment of kidney graft quality.

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