Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer.

Nele Loret,Niels Vandamme,Jordy De Coninck,Joachim Taminau, Kato De Clercq,Gillian Blancke,Sven Jonckheere,Steven Goossens,Kelly Lemeire,Sofie De Prijck,Kevin Verstaen,Ruth Seurinck,Jo Van Dorpe,Steven Weyers,Hannelore Denys,Koen Van de Vijver,Bart N Lambrecht,Philippe Tummers,Yvan Saeys,Geert Berx

Molecular cancer research : MCR（2022）

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摘要

The newly characterized differences between ascitic and solid cancer cells before and after chemotherapy could inform novel treatment strategies for metastatic HGSOC.

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关键词

cancer cells,solid cancer cells,chemotherapy,distinct transcriptional programs,high-grade

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