Influenza B: Prospects for the Development of Cross-Protective Vaccines
VIRUSES-BASEL(2022)
摘要
In this review, we analyze the epidemiological and ecological features of influenza B, one of the most common and severe respiratory infections. The review presents various strategies for cross-protective influenza B vaccine development, including recombinant viruses, virus-like particles, and recombinant proteins. We provide an overview of viral proteins as cross-protective vaccine targets, along with other updated broadly protective vaccine strategies. The importance of developing such vaccines lies not only in influenza B prevention, but also in the very attractive prospect of eradicating the influenza B virus in the human population.
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关键词
influenza B, virus, phylogenetic lineages, viral proteins, monoclonal antibodies, cross-protection vaccines
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