Abstract #1180332: IgG4-related Hypophysitis

Immunoglobulin G4-related disease (IgG4-RD) is a rare systemic fibro-inflammatory condition characterized by infiltration of tissue with IgG4-positive plasma cells. Several types of hypophysitis include Lymphocytic/autoimmune, granulomatous, xanthomatous, necrotizing, and plasmacytic/IgG4-related. We present a young female with history of secondary amenorrhea who was found to have IgG4-related hypophysitis based on tissue diagnosis. A mixed solid-cystic sellar mass is more commonly due to a craniopharyngioma or a pituitary adenoma.