C-40 | Outcomes of Transcatheter Aortic Valve Replacement stratified by Severity of Mitral Annular Calcification

BackgroundThere are limited data regarding the impact of mitral annular calcification (MAC) on the outcomes of patients undergoing transcatheter aortic valve replacement (TAVR).MethodsWe performed a retrospective analysis of patients who underwent TAVR in 2018 and divided them into 4 groups (absent, mild, moderate, and severe MAC) using a validated MAC CT-based scoring system.ResultsPatients with MAC were older (81 years vs. 78 years, p=0.012) and less likely male (53% vs 68%, p=0.002). They had higher BMI (29.4 vs 28.05, p=0.031) and higher frailty score (0.76 vs 0.67). There was no significant difference in the 1- and 2-year mortality after TAVR between the 4 groups (Table). Similarly, rates of new-onset 30-day pacemaker implantation, 30-day stroke, 1-year myocardial infarction, 1-year stroke and 1-year MACCE were comparable in all 4 groups. However, patients with severe MAC had a slightly higher rate of new-onset left bundle branch block in comparison to the other groups.ConclusionsDisclosuresH. M. Lak Nothing to disclose. S. Chawla Nothing to disclose. B. Verma Nothing to disclose. T. Ahmed Nothing to disclose. R. D. Gajulapalli Nothing to disclose. A. Agrawal Nothing to disclose. S. Kumar Nothing to disclose. F. Alkhalaileh Nothing to disclose. B. Ghimire Nothing to disclose. S. Shekhar Nothing to disclose. A. Bansal Nothing to disclose. R. Nair Nothing to disclose. J. Yun Nothing to disclose. S. Unai Nothing to disclose. G. Pettersson Nothing to disclose. G. W. Reed Nothing to disclose. R. Puri Nothing to disclose. A. Krishnaswamy Nothing to disclose. S. C. Harb Nothing to disclose. S. R. Kapadia Nothing to disclose. BackgroundThere are limited data regarding the impact of mitral annular calcification (MAC) on the outcomes of patients undergoing transcatheter aortic valve replacement (TAVR). There are limited data regarding the impact of mitral annular calcification (MAC) on the outcomes of patients undergoing transcatheter aortic valve replacement (TAVR). MethodsWe performed a retrospective analysis of patients who underwent TAVR in 2018 and divided them into 4 groups (absent, mild, moderate, and severe MAC) using a validated MAC CT-based scoring system. We performed a retrospective analysis of patients who underwent TAVR in 2018 and divided them into 4 groups (absent, mild, moderate, and severe MAC) using a validated MAC CT-based scoring system. ResultsPatients with MAC were older (81 years vs. 78 years, p=0.012) and less likely male (53% vs 68%, p=0.002). They had higher BMI (29.4 vs 28.05, p=0.031) and higher frailty score (0.76 vs 0.67). There was no significant difference in the 1- and 2-year mortality after TAVR between the 4 groups (Table). Similarly, rates of new-onset 30-day pacemaker implantation, 30-day stroke, 1-year myocardial infarction, 1-year stroke and 1-year MACCE were comparable in all 4 groups. However, patients with severe MAC had a slightly higher rate of new-onset left bundle branch block in comparison to the other groups. Patients with MAC were older (81 years vs. 78 years, p=0.012) and less likely male (53% vs 68%, p=0.002). They had higher BMI (29.4 vs 28.05, p=0.031) and higher frailty score (0.76 vs 0.67). There was no significant difference in the 1- and 2-year mortality after TAVR between the 4 groups (Table). Similarly, rates of new-onset 30-day pacemaker implantation, 30-day stroke, 1-year myocardial infarction, 1-year stroke and 1-year MACCE were comparable in all 4 groups. However, patients with severe MAC had a slightly higher rate of new-onset left bundle branch block in comparison to the other groups. Conclusions DisclosuresH. M. Lak Nothing to disclose. S. Chawla Nothing to disclose. B. Verma Nothing to disclose. T. Ahmed Nothing to disclose. R. D. Gajulapalli Nothing to disclose. A. Agrawal Nothing to disclose. S. Kumar Nothing to disclose. F. Alkhalaileh Nothing to disclose. B. Ghimire Nothing to disclose. S. Shekhar Nothing to disclose. A. Bansal Nothing to disclose. R. Nair Nothing to disclose. J. Yun Nothing to disclose. S. Unai Nothing to disclose. G. Pettersson Nothing to disclose. G. W. Reed Nothing to disclose. R. Puri Nothing to disclose. A. Krishnaswamy Nothing to disclose. S. C. Harb Nothing to disclose. S. R. Kapadia Nothing to disclose. H. M. Lak Nothing to disclose. S. Chawla Nothing to disclose. B. Verma Nothing to disclose. T. Ahmed Nothing to disclose. R. D. Gajulapalli Nothing to disclose. A. Agrawal Nothing to disclose. S. Kumar Nothing to disclose. F. Alkhalaileh Nothing to disclose. B. Ghimire Nothing to disclose. S. Shekhar Nothing to disclose. A. Bansal Nothing to disclose. R. Nair Nothing to disclose. J. Yun Nothing to disclose. S. Unai Nothing to disclose. G. Pettersson Nothing to disclose. G. W. Reed Nothing to disclose. R. Puri Nothing to disclose. A. Krishnaswamy Nothing to disclose. S. C. Harb Nothing to disclose. S. R. Kapadia Nothing to disclose.