Triiodide ion-induced inhibition of amyloid aggregate formation: A case study of α-synuclein

Journal of Molecular Liquids(2022)

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摘要
•The effect of ethylammonium iodide (EAI) on the formation of amyloid aggregates of α-synuclein (α-SynA) was investigated.•Concentrated EAI solutions exhibited an ability to inhibit α-SynA formation.•The formation of triodide (I3–) ion in this media relates to the inhibition of α-SynA formation.•The inhibition ability of ammonium-based iodides for α-SynA formation are stronger than alkali-iodides.
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关键词
Inhibition,Triiodide ion,α-Synuclein,Amyloid aggregate,Spectroscopy
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