Three-dimensional phase and intensity tomography from coherent modulation imaging measurements

Coherent modulation imaging is a lensless imaging technique, where a complex-valued image can be recovered from a single diffraction pattern using the iterative algorithm. Although mostly applied in two dimensions, it can be tomographically combined to produce three-dimensional (3D) images. Here we present a 3D reconstruction procedure for the sample's phase and intensity from coherent modulation imaging measurements. Pre-processing methods to remove illumination probe, inherent ambiguities in phase reconstruction results, and intensity fluctuation are given. With the projections extracted by our method, standard tomographic reconstruction frameworks can be used to recover accurate quantitative 3D phase and intensity images. Numerical simulations and optical experiments validate our method.