New strategy in electrochemical investigation of DNA damage demonstrated on genotoxic derivatives of fluorene
Journal of Electroanalytical Chemistry（2022）
Abstract
•Electrochemical DNA biosensor based on a glassy carbon electrode was optimized and characterized.•Comprehensive electrochemical biosensing approach was used to detect DNA damage.•DNA damage was detected after interaction with derivatives of fluorene.•Simple electrochemical DNA biosensor was applied for fast and sensitive detection.•Investigation of derivatives of fluorene with dsDNA present in solution was used.
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Key words
Electrochemical DNA biosensor,Glassy carbon electrode,Derivatives of fluorene,Overlapping signals,Voltammetry,Electrochemical impedance spectroscopy,Scannnig electrochemical microscopy
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