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基于"肝体阴用阳"理论的肝纤维化分子生物学机制的中医内涵探讨

代静慧,肖准,马素平

Lishizhen Medicine and Materia Medica Research（2022）

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Abstract
肝纤维化表现为细胞外基质的沉积及瘢痕组织形成,其发病机理涉及肝细胞、肝星状细胞、肝窦内皮细胞、炎性细胞等多种肝脏细胞群."肝体阴用阳"是中医学关于肝脏基本功能及特点的系统总结,指导着中医临床肝病诊疗及用药.肝纤维化当治以滋阴养血,兼活血化瘀、益气健脾养肝等.而肝纤维化病理机制中的肝脏细胞群代谢功能异常和炎症稳态失衡可能与"肝体阴用阳"功能的破坏有关.
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