Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer

Parvathi A Myer,Hyunjin Kim,Anna M Blümel,Ellen Finnegan,Alexander Kel,Taylor V Thompson,John M Greally,Jochen Hm Prehn,Darran P O'Connor,Richard A Friedman,Aris Floratos,Sudipto Das

Gastro Hep Advances（2022）

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摘要

Our study provides an insight into the intricate regulatory landscape of MTRs and TFs that orchestrate the differences in the tumor microenvironment between patients with CRC of AFR and EUR ancestry.

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Health Disparities,Colorectal Cancer,Genomic Profiling,African Americans.

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