Visuo-motor transformations in the intraparietal sulcus mediate the acquisition of endovascular medical skill

•Acquiring the skills needed to conduct an endovascular intervention is associated with structural and functional brain changes in the intraparietal sulcus.•behavioural improvements on the endovascular task are related to connectivity changes between the visual cortex and bi-lateral clusters in the intraparietal sulcus.•Individual differences in grey matter volume of cerebellar Lobule VIIIb predict participants’ overall performance in this newly acquired medical skill.