Dual inhibition of autophagy and PI3K/mTOR pathway as a potential therapeutic strategy against laryngeal squamous cell carcinoma.

Hui-Ying Huang,Ke-Nan Li,Hui-Ching Lau,Chi-Yao Hsueh,Ning Cong,Ming Zhang

Translational cancer research（2022）

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摘要

NVP-BEZ235 exerted potent antitumor effects on LSCC, especially when combined with the autophagy inhibitor both and , providing convincing experimental data for new molecular targeted therapy for LSCC.

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关键词

Laryngeal squamous cell carcinoma (LSCC),PI3K/mTOR inhibitors,autophagy

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