The Intact Noninducible Latent HIV-1 Reservoir Is Established in an In Vitro Primary T _CM Cell Model of Latency

Indra Sarabia,Szu-Han Huang,Adam R. Ward,R. Brad Jones,Alberto Bosque

Journal of Virology（2021）

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Abstract

HIV-1 establishes a latent reservoir that persists under antiretroviral therapy. Antiretroviral therapy is able to stop the spread of the virus and the progression of the disease but does not target this latent reservoir.

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The Intact Noninducible Latent HIV-1 Reservoir Is Established in an In Vitro Primary T CM Cell Model of Latency

The Intact Noninducible Latent HIV-1 Reservoir Is Established in an In Vitro Primary T _CM Cell Model of Latency