Inhibition of Radioactive Depletion of Hemocytes and Antitumor Effects of Flavonoid
Archives of Clinical and Medical Case Reports(2021)
Abstract
Natural products are able to inhibit radiation effects and exert an antitumor effect with fewer adverse reactions; however, their antitumor effects are less than those of widely-used synthetic drugs. Flavonoid is a natural material that has attracting attention, and we extracted this material with alcohol and investigated the effect of continuous flavonoid administration on radioactivity-induced reduction of hemocytes, in addition to the antioxidant and antitum or effects of flavonoid. Following a 1-week adjustment period, flavonoid was administered intraperitoneally to male ICR mice at a dose of 100 mg/kg every other day for 2 weeks.
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Key words
antitumor effects,hemocytes,radioactive depletion
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