Involvement of microRNA-133a-3p with the conversion of muscle fiber type in human skeletal myogenesis.

Zhou Yuhang,Yoshinori Ichihara,Hirotaka Iwasaki,Agung Kurniawan Priyono,Tatsuya Sawano,Keiko Nagata,Junichiro Miake,Hidetoshi Sakurai,Takeshi Imamura

Proceedings for Annual Meeting of The Japanese Pharmacological Society（2021）

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Abstract

Objective: Skeletal muscle fiber conversion bears a part in multiple myopathies, and one of those is Sarcopenia which is known to correlate with aging, nutritional deficiency, and so on. In this study, we focused on muscle specific enriched microRNAs (myomirs) to understand the mechanisms of muscle fiber conversion.

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Key words

human skeletal myogenesis,muscle fiber type

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