Abstract #994705: The High Prevalence of Coronary Calcification and Increased Risk for Coronary Heart Disease in Patients with Sheehan’s Syndrome

Sheehan's syndrome (SS) is one of the most important causes of hypopituitarism in developing countries with patients having varying degrees and severity of anterior pituitary hormone deficiency including growth hormone deficiency (GHD). SS is characterized by Increased clustering of metabolic and pro-inflammatory risk factors predisposing them to increased cardiovascular morbidity and mortality. Coronary calcium deposits (CCD), a marker for significant coronary atherosclerosis, is used for evaluation in asymptomatic individuals of global cardiac risk to develop events related to coronary heart disease (CHD). The present study was designed to evaluate the prevalence of coronary calcium deposits in patients with SS appropriately replaced for pituitary hormones deficiencies but untreated for GHD.