China-Zanzibar Cooperation Project of Schistosomiasis Control: Study Design

Schistosomiasis is a public health problem mostly in Africa. In 2014, World Health Organization (WHO) signed a tripartite memorandum of understanding (MOU) with China and Tanzania-Zanzibar paving the way for piloting interventions for schistosomiasis elimination in Zanzibar. The study has been designed including the transmission pattern of schistosomiasis; the effectiveness studies of praziquantel from China and mass drug administration (MDA) for suitable method of human treatment; biological study of snails and effectiveness of novel molluscicides from China in laboratory and field for the suitable method of snail control; KAP study and health education design for suitable method of behavior interventions by health education. The integrated measures will be implemented after baseline surveillance. At last, the effectiveness of the integrated measure will be evaluated by the index of snail density, prevalence, and KAP of human.