B-po03-123 relation between premature ventricular contraction origin, underlying heart disease and ablation outcome

Premature ventricular contractions (PVCs) in patients with structural heart disease (SHD) may be idiopathic but can also be related to the SHD. To evaluate PVC origins and acute outcome related to the presence of underlying structural heart disease. We retrospectively reviewed 290 procedures in 281 consecutive patients who underwent PVC ablation. The origin of PVC was defined by mapping and elimination by ablation. Acute success was defined as abolition of the target PVC. Of 281 patients, 174(62%) had SHD (coronary disease in 56, cardiomyopathy in 94, valve disease in 20, other in 4). Patients with SHD more often had PVC origin from the LV papillary muscles (28% vs 14%; P < 0.01) and less often PVCs from the RV outflow tract (RVOT) (18% vs 36%; P < 0.01) compared with patients with no SHD (table 1). Conducted sinus rhythm QRS duration was longer in SHD patients (104.8 vs 95.6ms; P < 0.01). Acute ablation success was similar between SHD and no SHD patients (90% vs 94%; P=0.24) and similar across PVC locations for patients with and without SHD. Complications were not different in patients with and without SHD (2 % vs 2%). SHD was present in 62% of patients referred for PVC ablation. Patients with SHD more often have PVC origin from LV papillary muscles and less often from the RVOT, but focal origin and high ablation success are similar to patients without SHD.