A Case of Severe Stenosis of the Esophageal Junction After Bio-radiation Therapy with Cetuximab for Hypopharyngeal Cancer

The standard treatment for locally advanced head and neck squamous cell carcinoma includes surgery, chemoradiotherapy (CRT), or bio-radiation therapy (BRT). BRT is recommended for elderly and patients with renal failure. However, acute mucositis, dermatitis, and dysphagia occur more frequently following BRT than after CRT. The incidence of esophageal stricture was significantly higher in patients who underwent percutaneous endoscopic gastrostomy (PEG) before treatment than in those who did not undergo PEG. We report a case of severe stenosis of the esophageal junction developing after BRT in a patient with hypopharyngeal cancer.