MP07-17 STONE ABLATION EFFICACY OF A NEW PROTOTYPE HOLMIUM:YAG PULSE-MODULATED LASER AT WORKING DISTANCES OF UP TO 3 mm

You have accessJournal of UrologyStone Disease: Basic Research & Pathophysiology (MP07)1 Sep 2021MP07-17 STONE ABLATION EFFICACY OF A NEW PROTOTYPE HOLMIUM:YAG PULSE-MODULATED LASER AT WORKING DISTANCES OF UP TO 3 mm Bingyuan Yang, Isha Parab, Jasmine Cancino, Sanwei Liu, Aditi Ray, Thomas Hasenberg, Tim Harrah, and Ben Turney Bingyuan YangBingyuan Yang More articles by this author , Isha ParabIsha Parab More articles by this author , Jasmine CancinoJasmine Cancino More articles by this author , Sanwei LiuSanwei Liu More articles by this author , Aditi RayAditi Ray More articles by this author , Thomas HasenbergThomas Hasenberg More articles by this author , Tim HarrahTim Harrah More articles by this author , and Ben TurneyBen Turney More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001980.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Holmium:YAG laser has been the lithotrite of choice for around 30 years in kidney stone surgery. The relatively high absorption in water is clinically useful but also limits the effective range of these lasers. Laser technology has taken advantage of the “Moses effect” to improve energy delivery to the target while reducing heating of the irrigation fluid. We report on a new prototype Holmium laser that fires multiple micro-pulses in pulse packets and present stone phantom ablation rate results at fiber-to-stone working distances of up to 3mm utilizing a bench model. METHODS: Uniform, homogeneous BegoStones (15:3 BegoStone:water) were used. A 242mm core fiber was attached to the prototype laser and the fiber was moved over the surface of the stone in a predetermined pattern using an automated system. A range of pulse packet energy/frequency settings from 20 W to 45 W were investigated. Stone ablation efficiency was measured by dry-weight difference before and after treatment. A range of working distances (WDs) from 0.5 mm to 3 mm were used to investigate the effect of increased distance to the stone. RESULTS: Measurable ablation rates were observed with the prototype pulse-modulated laser up to a working distance of 3 mm, across a range of powers (figure 1). The ablation rate at 3 mm WD was 27.6% of that at 0.5 mm WD (range 12.9-44.4%). Results from a reference holmium laser using the same methodology are also included. CONCLUSIONS: The prototype laser demonstrated an impressive working range in our bench testing across a range of power settings, with measurable ablation even at a WD of 3 mm. This suggests that these micro-pulses produce a significant Moses effect. We feel that pulse-modulation with packets of micro-pulses can synergise well with the Moses effect to increase the effective range and needs to be further tested in a clinical setting. (Disclaimer: Concept device or technology. Not available for sale). Source of Funding: Boston Scientific Corp © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e146-e146 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Bingyuan Yang More articles by this author Isha Parab More articles by this author Jasmine Cancino More articles by this author Sanwei Liu More articles by this author Aditi Ray More articles by this author Thomas Hasenberg More articles by this author Tim Harrah More articles by this author Ben Turney More articles by this author Expand All Advertisement Loading ...