Systems pharmacology-based mechanism exploration of Acanthopanax senticosusin for Alzheimer's disease using UPLC-Q-TOF-MS, network analysis, and experimental validation.

Yue Zhuo,Xiaomei Fu,Qiyao Jiang,Yiyi Lai, Yong Gu,Shuhuan Fang,Huiling Chen,Chenchen Liu,Huafeng Pan,Qihui Wu,Jiansong Fang

European journal of pharmacology（2023）

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摘要

Overall, this study applied systems pharmacology approach, via UPLC-Q-TOF-MS, network analysis, and experimental validation to decipher the potential molecular mechanism of AS against AD.

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关键词

Alzheimer disease, Acanthopanax senticosusin, UPLC-Q-TOF-MS, Systems pharmacology, In vivo

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