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Randomised trial of block and replace vs. dose titration thionamide in young people with thyrotoxicosis

Wood CL,Cole M,Donaldson M, Dunger DB,Wood R,Morrison N, Matthews JNS,Pearce SHS,Cheetham TD

Yearbook of Paediatric Endocrinology（2021）

Cited 8|Views3
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Abstract
This study provides for the first time clear evidence that the block and replace (BR) strategy (combination of carbimazole plus levothyroxine) is not superior to the carbimazole dose titration (DT) strategy for treatment of paediatric Graves’ disease.
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Key words
dose titration thionamide
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